Kaltzifediol

Kaltzifediol
Formula kimikoa	C27H44O2
SMILES kanonikoa	2D eredua
SMILES isomerikoa	C[C@H](CCCC(C)(C)O)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C3\C[C@@H](O)CCC3=C
MolView	3D eredua
Mota	D3 vitamins (en) , Sekoesteroide eta 9,10-secocholestane steroid (en)
Estereoisomeroa	(5E,7Z)-(3S)-9,10-seco-5,7,10(19)-cholestatriene-3,25-diol (en) , (5Z,7E)-(3R)-9,10-seco-5,7,10(19)-cholestatriene-3,25-diol (en) , [[(1S)-3-[2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol\|(1S)-3-[2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol]] (en) , (5Z,7E)-(3S)-9,10-seco-5,7,10(19)-cholestatriene-3,25-diol (en) , 5,6-trans-25-hydroxyvitamin D3 (en) , 5-trans-25-hydroxycholecalciferol (en) eta 3-epi-25-Hydroxyvitamin D3 (en)
Masa molekularra	400,334 Da
Erabilera
Tratatzen du	metabolic bone disease (en) , vitamin D deficiency (en) eta secondary hyperparathyroidism of renal origin (en)
Elkarrekintza	cytochrome P450 family 2 subfamily R member 1 (en)
Rola	primary metabolite (en)
Identifikatzaileak
InChlKey	JWUBBDSIWDLEOM-DTOXIADCSA-N
CAS zenbakia	19356-17-3
ChemSpider	4446820
PubChem	5283731
Reaxys	4270041
Gmelin	17933
ChEMBL	CHEMBL1040
EC zenbakia	242-990-9
ECHA	100.039.067
MeSH	D002112
RxNorm	1855064
Human Metabolome Database	HMDB0003550
UNII	T0WXW8F54E
NDF-RT	N0000146836
KEGG	C01561
PDB Ligand	VDY

Kaltzifediola, kaltzidiola, 25-hidroxikolekaltziferola edo 25-hidroxibitamina D₃ (25(OH)D₃ laburtua),^[1] gibelean D3 bitaminaren hidroxilazioaren bidez sortzen den prohormona da. Kaltzifediola, orduan, (25(OH)D-1α-hidroxilasa entzimaren eraginez) giltzurrunetan kaltzitriol (1,25-(OH)₂D3) bihurtzen da,^[2] D bitaminaren forma aktiboa den hormona sekoesteroidea. Giltzurrunetan 24-hidroxikalazioaren eraginez 24-hidroxikaltzidiol ere bihur daiteke.