Nerbio hazkunde-faktore

Identifikadoreak
Taxoia	Homo sapiens
Kokapena
Hasiera
Amaiera
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Transkripzioak
Gene-adierazpen eredua
Ontologia
Funtzio-molekularrak	Ikusi peptidase inhibitor activity (en) ; enzyme inhibitor activity (en) ; proteina lotura; metalloendopeptidase inhibitor activity (en) ; nerve growth factor receptor binding (en) ; growth factor activity (en) ; signaling receptor binding (en) ; nerve growth factor receptor binding (en) ;
Osagai-zelularra	Ikusi endosoma; Golgi lumen (en) ; zelulaz kanpoko eremu; cytoplasmic vesicle (en) ; zelulaz kanpoko eremu; extracellular space (en) ; zitosol; synaptic vesicle (en) ; Axoi; Dendrita;
Prozesu-biologikoak	Ikusi negative regulation of neuron apoptotic process (en) ; regulation of neuron differentiation (en) ; neuron projection morphogenesis (en) ; negative regulation of peptidase activity (en) ; neurotrophin TRK receptor signaling pathway (en) ; cell-cell signaling (en) ; negative regulation of apoptotic process (en) ; regulation of cysteine-type endopeptidase activity involved in apoptotic process (en) ; positive regulation of axonogenesis (en) ; positive regulation of gene expression (en) ; positive regulation of apoptotic process (en) ; nerve growth factor processing (en) ; extrinsic apoptotic signaling pathway via death domain receptors (en) ; phosphatidylinositol-mediated signaling (en) ; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process (en) ; microtubule-based movement (en) ; activation of cysteine-type endopeptidase activity involved in apoptotic process (en) ; positive regulation of Ras protein signal transduction (en) ; transmembrane receptor protein tyrosine kinase signaling pathway (en) ; peripheral nervous system development (en) ; Oroimen; negative regulation of cell population proliferation (en) ; regulation of signaling receptor activity (en) ; positive regulation of gene expression (en) ; nerve development (en) ; nerve growth factor signaling pathway (en) ; positive regulation of DNA binding (en) ; positive regulation of neuron differentiation (en) ; positive regulation of collateral sprouting (en) ; neuron projection morphogenesis (en) ; modulation of chemical synaptic transmission (en) ;

Nerbio hazkunde-faktore (NGF) faktore neotrofiko eta neuropeptido bat da, neurona zehatz batzuen hazkuntza, mantenu, hedatze eta biziraupenean parte-hartzen duena. Ziurrenik hazkunde-faktore prototipoa da, eta deskribatu zen lehenetako bat izan zen. Rita Levi-Montalcini eta Stanley Cohenek 1956an isolatu eta Medikuntzako Nobel Saria eskuratu zuten. Garai hartatik hainbat prozesu biologiko aurkitu dira NGFk parte-hartzen duena, horietako bi pankreako beta-zelulen biziraupena eta sistema-immunitarioaren erregulazioa izanik.

Azken urteotako ikerketak aurkitu du NGFren kontzentrazioa odol plasman handiagoa dela harreman erromantiko bat izan dutenen artean 12 hilabete baino gehiagoz, izan ez dutenengan baino^[3].

Erreferentziak[aldatu | aldatu iturburu kodea]

↑ GRCh38: Ensembl release 89:. Ensembl.
↑ GRCh38: Ensembl release 89:. Ensembl.
↑ EMANUELE, E; POLITI, P; BIANCHI, M; MINORETTI, P; BERTONA, M; GEROLDI, D. «Raised plasma nerve growth factor levels associated with early-stage romantic love» Psychoneuroendocrinology 31 (3): 288–294. doi:10.1016/j.psyneuen.2005.09.002. (Noiz kontsultatua: 2017-10-23).

Kanpo estekak[aldatu | aldatu iturburu kodea]

Datuak: Q417782
Multimedia: Nerve growth factors / Q417782

[1] GRCh38: Ensembl release 89:. Ensembl.

[2] GRCh38: Ensembl release 89:. Ensembl.

[3] EMANUELE, E; POLITI, P; BIANCHI, M; MINORETTI, P; BERTONA, M; GEROLDI, D. «Raised plasma nerve growth factor levels associated with early-stage romantic love» Psychoneuroendocrinology 31 (3): 288–294. doi:10.1016/j.psyneuen.2005.09.002. (Noiz kontsultatua: 2017-10-23).

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